Article
Nonviral Delivery Systems for Cancer Gene Therapy: Strategies and Challenges.
Current gene therapy - 1 Jan 2018
Shim Gayong, Kim Dongyoon, Le Quoc-Viet, Park Gyu Thae, Kwon Taekhyun, Oh Yu-Kyoung
Abstract excerpt
Gene therapy has been receiving widespread attention due to its unique advantage in regulating the expression of specific target genes. In the field of cancer gene therapy, modulation of gene expression has been shown to decrease oncogenic factors in cancer cells or increase immune responses against cancer. Due to the macromolecular size and highly negative physicochemical features of plasmid DNA, efficient...
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