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Distinguishing Between Mouse and Human Pluripotent Stem Cell Regulation: The Best Laid Plans of Mice and Men

6 Jan 2010

Abstract excerpt

Pluripotent stem cells (PSCs) have been derived from the embryos of mice and humans, representing the two major sources of PSCs. These cells are universally defined by their developmental properties, specifically their self-renewal capacity and differentiation potential which are regulated in mice and humans by complex transcriptional networks orchestrated by conserved transcription factors. However, significant...

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CRISPR and Genetic Engineering
Pluripotent Stem Cells Research
Tissue Engineering and Regenerative Medicine

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20054863
DOI: 10.1002/stem.298

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