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Genetic evolution and cellular interactions within the tumour microenvironment determine glioblastoma progression

2023-01-13

Abstract excerpt

Glioblastoma (GBM) is the most aggressive form of primary brain cancer, with 5-year survival rates of less than 5%. Clinical management of GBM has not changed in the last 15 years, and current treatment approaches combine surgical resection, followed by radiotherapy and chemotherapy. Tragically, tumour recurrence is inevitable. Still, very little is known about how tumours evolve in response to therapy and become...

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Literature Corpus work
11772e9c-7016-54b5-a26b-46f709d90e45
DOI
10.12688/f1000research.129089.1
Open publication

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Genetic evolution and cellular interactions within the tumour microenvironment determine glioblastoma progressionDOI 10.12688/f1000research.129089.1
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