Back to search

Article

The role of XPB/Ssl2 dsDNA translocation processivity in transcription-start-site scanning

2020-11-10

Abstract excerpt

The general transcription factor TFIIH contains three ATP-dependent catalytic activities. TFIIH functions in nucleotide excision repair primarily as a DNA helicase and in Pol II transcription initiation as a dsDNA translocase and protein kinase. During initiation, the XPB/Ssl2 subunit of TFIIH couples ATP hydrolysis to dsDNA translocation facilitating promoter opening and the kinase module phosphorylates the C-ter...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
2c2d4708-1cf3-57b1-8985-473ecf14316f
DOI
10.1101/2020.11.09.375329
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The role of XPB/Ssl2 dsDNA translocation processivity in transcription-start-site scanningDOI 10.1101/2020.11.09.375329
A history of TFIIH: two decades of molecular biology on a pivotal transcription/repair factor.Semantic proximity
Tfb6, a previously unidentified subunit of the general transcription factor TFIIH, facilitates dissociation of Ssl2 helicase after transcription initiation.Semantic proximity
Function of Conserved Topological Regions within the Saccharomyces cerevisiae Basal Transcription Factor TFIIH.Semantic proximity
Ssl2/TFIIH function in Transcription Start Site Scanning by RNA Polymerase II in <i>Saccharomyces cerevisiae</i>Semantic proximity
Nucleotide Excision Repair and Transcriptional Regulation: TFIIH and Beyond.Semantic proximity
Structural basis of TFIIH activation for nucleotide excision repairSemantic proximity
The complete structure of the human TFIIH core complexSemantic proximity
The Role of TFIIH Complex in Nucleotide Excision RepairSemantic proximity
The essential and multifunctional TFIIH complexSemantic proximity
Mechanism of start site selection by RNA polymerase II: interplay between TFIIB and Ssl2/XPB helicase subunit of TFIIH.Semantic proximity
Transcription without XPB Establishes a Unified Helicase-Independent Mechanism of Promoter Opening in Eukaryotic Gene Expression.Semantic proximity
Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH.Semantic proximity
Select a neighboring publication to make it the new centre.