Article

Identification of common variants influencing risk of the three-repeat tauopathy Pick’s disease: a genome wide association study

2025-12-27

Abstract excerpt

Pick’s disease (PiD) is a rare cause of sporadic frontotemporal dementia, neuropathologically defined by the presence of Pick bodies consisting of aggregates of 3-repeat tau. Given the genetic aetiology of PiD remains unresolved, we assembled the Pick’s disease International Consortium (PIC) to identify susceptibility loci through a genome-wide association study (GWAS). A GWAS was conducted in 294 autopsy confirme...

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Literature Corpus work: d6a9594a-10b5-572f-af1b-7ac79a6e25df
DOI: 10.64898/2025.12.21.25342758

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