Article

<i>TMEM175, SCARB2</i> and <i>CTSB</i> associations with Parkinson’s disease risk across populations

2025-08-24

Abstract excerpt

Genome-wide association study of Parkinson’s disease (PD) identified common variants associated with lysosomal mechanism, including TMEM175, SCARB2 , and CTSB . We investigated the association between common and rare variants across populations using cohorts from the Global Parkinson’s Genetics Program (GP2) (33,813 cases and 18,714 controls from 11 ancestries), and the Accelerating Medicines Partnership Parkinson...

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Literature Corpus work: 9bcaf483-7b26-5138-a6fd-e7dbfcfbae80
DOI: 10.1101/2025.08.17.25333823

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