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Genome Wide Association Study and Next Generation Sequencing: A Glimmer of Light Toward New Possible Horizons in Frontotemporal Dementia Research

16 May 2019

Abstract excerpt

Frontotemporal Dementia (FTD) is a focal neurodegenerative disease with a strong genetic background, that causes early onset dementia. The present knowledge about the risk loci and causative mutations of FTD mainly derives from genetic linkage analysis, studies of candidate genes, Genome-Wide Association Studies (GWAS) and Next-Generation Sequencing (NGS) applications. In this review we report recent insights...

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PMID: 31156380
DOI: 10.3389/fnins.2019.00506

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