Article

Large-scale Rare Variant Burden Testing in Parkinson’s Disease Identifies Novel Associations with Genes Involved in Neuro-inflammation

2022-11-10

Abstract excerpt

Parkinson’s disease (PD) has a large heritable component and genome-wide association studies to date have identified over 90 variants associated with PD, providing deeper insights into the disease biology. However, there have not been large-scale rare variant analyses for PD. To address this gap, we investigated the rare genetic component of PD at minor allele frequencies <1%, using whole genome and whole exome se...

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Literature Corpus work: 4679291c-45e2-5884-938e-3a8e54cfda9b
DOI: 10.1101/2022.11.08.22280168

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