Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study

15 Apr 2024

Abstract excerpt

BACKGROUND: Pick's disease is a rare and predominantly sporadic form of frontotemporal dementia that is classified as a primary tauopathy. Pick's disease is pathologically defined by the presence in the frontal and temporal lobes of Pick bodies, composed of hyperphosphorylated, three-repeat tau protein, encoded by the MAPT gene. MAPT has two distinct haplotypes, H1 and H2; the MAPT H1 haplotype is the major...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Amyotrophic Lateral Sclerosis Research
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38631765
DOI: 10.1016/s1474-4422(24)00083-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association studyPMID 38631765Read ↗

Creating the Pick’s disease International Consortium: Association study of<i>MAPT</i>H2 haplotype with risk of Pick’s diseaseSemantic proximity Read ↗

Identification of common variants influencing risk of the three-repeat tauopathy Pick’s disease: a genome wide association studySemantic proximity Read ↗

MAPT haplotype H1G is associated with increased risk of dementia with Lewy bodies.Semantic proximity Read ↗

Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration.Semantic proximity Read ↗

MAPT Haplotype Variation and Alzheimer's Disease Risk: A Narrative Review with Focus on the Jordanian Population.Semantic proximity Read ↗

Navigating the ALS Genetic Labyrinth: The Role of MAPT Haplotypes.Semantic proximity Read ↗

MAPT Locus in Parkinson's Disease Patients of Ashkenazi Origin: A Stratified Analysis.Semantic proximity Read ↗

MAPT subhaplotypes in corticobasal degeneration: assessing associations with disease risk, severity of tau pathology, and clinical features.Semantic proximity Read ↗

Dementia risk in Parkinson disease: disentangling the role of MAPT haplotypes.Semantic proximity Read ↗

Genome-wide association study stratified by<i>MAPT</i>haplotypes identifies potential novel loci in Parkinson’s diseaseSemantic proximity Read ↗

Role of MAPT mutations and haplotype in frontotemporal lobar degeneration in Northern Finland.Semantic proximity Read ↗

Exploring MAPT-containing H1 and H2 haplotypes in Parkinson’s disease across diverse populationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.