Article

Integrative Ranking Of Enhancer Networks Facilitates The Discovery Of Epigenetic Markers In Cancer

2020-11-26

Abstract excerpt

Regulation of gene expression through multiple epigenetic components is a highly combinatorial process. Alterations in any of these layers, as is commonly found in cancer diseases, can lead to a cascade of downstream effects on tumor suppressor or oncogenes. Hence, deciphering the effects of epigenetic alterations on regulatory elements requires innovative computational approaches that can benefit from the huge am...

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Literature Corpus work: d69b4f41-af6e-56ca-b3f3-7cbc81012c2b
DOI: 10.1101/2020.11.25.397844

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