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Human enhancers harboring specific sequence composition, activity, and genome organization are linked to the immune response

2016-09-30

Abstract excerpt

The FANTOM5 consortium recently characterized 65,423 human enhancers from 1,829 cell and tissue samples using the Cap Analysis of Gene Expression technology. We showed that the guanine and cytosine content at enhancer regions distinguishes two classes of enhancers harboring distinct DNA structural properties at flanking regions. A functional analysis of their predicted gene targets highlighted one class of enhance...

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Literature Corpus work
e62e8edc-0713-58da-8a4c-766bffe7017f
DOI
10.1101/078477
Open publication

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Human enhancers harboring specific sequence composition, activity, and genome organization are linked to the immune responseDOI 10.1101/078477
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