Article

Long-read sequencing maps transposable element variation and its regulatory and epigenetic effects in the human brain

2026-07-03

Abstract excerpt

Transposable elements (TEs) are mobile DNA sequences that shape genome architecture and gene regulation, yet their roles in the human brain remain largely unresolved. Short-read sequencing lacks the resolution to accurately map TE insertions, detect associated structural variants, and resolve highly repetitive regions. Here, we leverage long-read whole-genome sequencing to profile germline TE insertions in postmor...

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Literature Corpus work: bbf8bb33-1903-50f7-ba53-0f4f7455af71
DOI: 10.64898/2026.07.02.735893

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