Article

Activated interstitial macrophages are a predominant target of viral takeover and focus of inflammation in COVID-19 initiation in human lung

2022-05-10

Abstract excerpt

<h4>ABSTRACT</h4> Early stages of deadly respiratory diseases such as COVID-19 have been challenging to elucidate due to lack of an experimental system that recapitulates the cellular and structural complexity of the human lung while allowing precise control over disease initiation and systematic interrogation of molecular events at cellular resolution. Here we show healthy human lung slices cultured ex vivo can...

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Literature Corpus work: bfeda998-d6c8-508f-8dec-9868960acd00
DOI: 10.1101/2022.05.10.491266

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