Article

Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity

2023-06-20

Abstract excerpt

<h4>SUMMARY</h4> Plasma RNAemia, delayed antibody responses and inflammation predict COVID-19 outcomes, but the mechanisms underlying these immunovirological patterns are poorly understood. We profile 782 longitudinal plasma samples from 318 hospitalized COVID-19 patients. Integrated analysis using k-means reveal four patient clusters in a discovery cohort: mechanically ventilated critically-ill cases are subdivi...

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Literature Corpus work: e1fc5895-6d58-58c2-90fd-d795abfccfc4
DOI: 10.1101/2023.06.14.23290814

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