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<i>O</i> -fucosylation of thrombospondin-like repeats is required for processing of MIC2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites

2018-08-01

Abstract excerpt

Toxoplasma gondii is an intracellular parasite that causes disseminated infections which can lead to neurological damage in fetuses and immunocompromised individuals. Microneme protein 2 (MIC2) 2 , a member of the thrombospondin-related anonymous protein (TRAP) family, is a secreted protein important for motility, host cell attachment, invasion, and egress. MIC2 contains six thrombospondin type I repeats (TSRs) t...

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Literature Corpus work
d5da2f2c-08d0-5b30-9bc0-ebbefc31922b
DOI
10.1101/382515
Open publication

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