Article
A cleavable propeptide influences Toxoplasma infection by facilitating the trafficking and secretion of the TgMIC2-M2AP invasion complex.
Molecular biology of the cell - 1 Oct 2006
Harper Jill M, Huynh My-Hang, Coppens Isabelle, Parussini Fabiola, Moreno Silvia, Carruthers Vern B
Abstract excerpt
Propeptides regulate protein function and trafficking in many eukaryotic systems and have emerged as important features of regulated secretory proteins in parasites of the phylum Apicomplexa. Regulated protein secretion from micronemes and host cell invasion are inextricably linked and essential processes for the apicomplexan parasite Toxoplasma gondii. TgM2AP is a propeptide-containing microneme protein found in...
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