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Article

Structural basis of Toxoplasma gondii MIC2-associated protein interaction with MIC2.

The Journal of biological chemistry - 16 Jan 2015

Huynh My-Hang, Liu Bing, Henry Maud, Liew Lloyd, Matthews Stephen J, Carruthers Vern B

Abstract excerpt

Toxoplasma gondii parasites must actively invade host cells to propagate. Secretory microneme proteins have been shown to be important for both gliding motility and active invasion. MIC2-M2AP is a protein complex that is essential for productive motility and rapid invasion by binding to host cell surface receptors. To investigate the architecture of the MIC2 and M2AP complex, we identified the minimal domains...

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Identifiers

PMID: 25411252
DOI: 10.1074/jbc.M114.613646
PMCID: PMC4340390

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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