Article

Ultrastructural and Molecular Analysis of Vascular Smooth Muscle Cells During the Switch from a Physiological to a Pathological Phenotype

2025-03-27

Abstract excerpt

<h4>Background: </h4> /Objectives: Under physiological conditions, vascular smooth muscle cells (VSMCs) are in a quiescent contractile state, but under pathological conditions, such as atherosclerosis, they change their phenotype to synthetic, characterized by increased proliferation, migration, and production of extracellular matrix. Furthermore, VSMCs can undergo calcification, switching to an osteoblast-like ph...

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Literature Corpus work: d5b2bad2-3e3b-5373-ad65-2cb88617eb36
DOI: 10.20944/preprints202503.2115.v1

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