Article
Vascular smooth muscle cell phenotypic plasticity and the regulation of vascular calcification.
Journal of internal medicine - 1 Sept 2006
Iyemere V P, Proudfoot D, Weissberg P L, Shanahan C M
Abstract excerpt
Vascular smooth muscle cells (VSMCs) exhibit an extraordinary capacity to undergo phenotypic change during development, in vitro and in association with disease. Unlike other muscle cells they do not terminally differentiate. Development and maintenance of the mature contractile phenotype is regulated by a number of interacting transcription factors. In response to injury contractile VSMCs can be induced to...
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