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Neuroprotective potential of intranasally delivered L-myc immortalized human neural stem cells in female rats after a controlled cortical impact injury

2023-09-05

Abstract excerpt

Efficacious stem cell-based therapies for traumatic brain injury (TBI) depend on successful delivery, migration, and engraftment of stem cells to induce neuroprotection. L-myc expressing human neural stem cells (LMNSC008) demonstrate an inherent tropism to injury sites after intranasal (IN) administration. We hypothesize that IN delivered LMNSC008 cells migrate to primary and secondary injury sites and modulate bi...

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Literature Corpus work
d5a657bd-50b5-559b-b046-f03d8b0fb630
DOI
10.21203/rs.3.rs-3242570/v1
Open publication

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Neuroprotective potential of intranasally delivered L-myc immortalized human neural stem cells in female rats after a controlled cortical impact injuryDOI 10.21203/rs.3.rs-3242570/v1
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