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Extracellular Vesicles Derived from L-MYC Neural Stem Cells Mediate Neuroprotection in 3D Models of Chemotherapy- and Radiation-Induced Neurotoxicity

2026-08-28

Abstract excerpt

<h4>Background: </h4> /Objectives: Cancer survivors frequently experience long-term neurocognitive impairments following chemotherapy and cranial irradiation, yet experimental models that enable mechanistic investigation of therapy-induced neurotoxicity at the transcriptional level remain limited. This study aimed to develop a human three-dimensional (3D) neural tissue model derived from L-Myc immortalized neural...

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Literature Corpus work: 53728641-7165-5a27-998f-c5ad794dd24e
DOI: 10.64898/2026.08.26.747380

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