Article
Enriching neural stem cell and anti-inflammatory glial phenotypes with electrical stimulation after traumatic brain injury in male rats.
Journal of neuroscience research - 1 Jul 2021
Park Eunyoung, Lyon Johnathan G, Alvarado-Velez Melissa, Betancur Martha I, Mokarram Nassir, Shin Jennifer H, Bellamkonda Ravi V
Abstract excerpt
Traumatic brain injury (TBI) by an external physical impact results in compromised brain function via undesired neuronal death. Following the injury, resident and peripheral immune cells, astrocytes, and neural stem cells (NSCs) cooperatively contribute to the recovery of the neuronal function after TBI. However, excessive pro-inflammatory responses of immune cells, and the disappearance of endogenous NSCs at the...
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