Article
Development of a human neural stem cell line for use in recovery from disability after stroke.
Frontiers in bioscience : a journal and virtual library - 1 Jan 2008
Stroemer Paul, Hope Andrew, Patel Sara, Pollock Kenny, Sinden John
Abstract excerpt
A clonal human neural stem cell line (ReN001) has been developed for clinical use in the treatment of stable disability after stroke. This cell line has been conditionally immortalized using the fusion transgene c-mycERTAM to allow controlled expansion when cultured in the presence of 4-hydroxytamoxifen. The cell line has been banked and fully characterized to assure there is genetic stability and no phenotypic...
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