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Macrophage Migration Inhibitory Factor (MIF) Overexpression Induced by SARS-CoV-2 Infection Promotes Neural Regeneration in Human Brain Organoids

2026-02-16

Abstract excerpt

While SARS-CoV-2 primarily targets the respiratory system, its neurological effects have become a significant clinical concern. Postmortem analyses reveal astrogliosis, neuronal death, and blood-brain barrier dysfunction, yet the interplay between neural injury and endogenous repair remains unclear. Here, we employed human embryonic stem cell–derived brain organoids to examine viral tropism, bystander effects, and...

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Literature Corpus work
91d87f08-77ee-59ae-beaa-43b794cf5b51
DOI
10.64898/2026.02.13.705720
Open publication

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Macrophage Migration Inhibitory Factor (MIF) Overexpression Induced by SARS-CoV-2 Infection Promotes Neural Regeneration in Human Brain OrganoidsDOI 10.64898/2026.02.13.705720
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