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An enhancer-centric approach applied to human immune system epigenomes revealed the association of macrophage enhancers with cardiovascular disease

2026-06-05

Abstract excerpt

Complex diseases are influenced by both genetic and environmental factors. Immune cells are key mediating interactions with the environment, but the impact of genetic variation on the immune system and how it influences complex diseases is not fully understood. Moreover, most genome-wide analyses (GWAS) variants associated with complex diseases are non-coding and difficult to interpret. Here, we investigated the a...

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Literature Corpus work
d59ac2f7-a9e5-50cc-bebe-01b8cbc73a9d
DOI
10.64898/2026.06.02.728745
Open publication

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An enhancer-centric approach applied to human immune system epigenomes revealed the association of macrophage enhancers with cardiovascular diseaseDOI 10.64898/2026.06.02.728745
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