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Article

Widespread translational remodeling during human neuronal differentiation

2017-06-26

Abstract excerpt

Faithful cellular differentiation requires precise coordination of changes in gene expression. However, the relative contributions of transcriptional and translational regulation during human cellular differentiation are unclear. Here, we induced forebrain neuronal differentiation of human embryonic stem cells (hESCs) and characterized genomewide RNA and translation levels during neurogenesis. We find that thousan...

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Literature Corpus work
d57ae690-eab7-5f90-a8d4-eb4e82f38e1c
DOI
10.1101/156190
Open publication

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Widespread translational remodeling during human neuronal differentiationDOI 10.1101/156190
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