Article

Integrated transcriptome and proteome analysis in human brain organoids reveals posttranscriptional regulation of ribosomal genes

2022-10-07

Abstract excerpt

During development of the human cerebral cortex, multipotent neural progenitors generate excitatory neurons and glial cells. Investigations of the transcriptome and epigenome have revealed important gene regulatory networks underlying this crucial developmental event. However, the post-transcriptional control of gene expression and protein abundance during human corticogenesis remains poorly understood. We address...

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Literature Corpus work: 0eb202e4-df8a-541a-82a3-eae395500998
DOI: 10.1101/2022.10.07.511280

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