Article

Transcriptome-wide alternative mRNA splicing analysis reveals post-transcriptional regulation of neuronal differentiation

2024-07-18

Abstract excerpt

Alternative splicing (AS) plays important roles in neuronal development, function, and diseases. Efforts to analyze AS transcriptome-wide in neurons remain limited. We characterized the transcriptome-wide AS changes in SH-SY5Y neuronal differentiation model, which is widely used to study neuronal function and disorders. Our analysis revealed global changes in five AS programs that drive neuronal differentiation. M...

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Literature Corpus work: 19916cb7-243a-5cb1-af8a-ebd1c3fc188a
DOI: 10.1101/2024.07.16.603656

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