Article

Centromeres and pericentromeric heterochromatin are accessible in living <i>Schizosaccharomyces pombe</i> cells

2025-12-15

Abstract excerpt

Chromatin is intrinsically repressive, limiting access to DNA, implying a major regulatory role. Studies with nuclei support this model. However, we have shown previously that genomic DNA is almost completely accessible in living budding yeast and human cells, except for centromeric chromatin. The fission yeast, Schizosaccharomyces pombe , possesses heterochromatin similar to mammalian heterochromatin at the peri...

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Literature Corpus work: d563208d-3416-58dc-aedf-b1e6d689e09b
DOI: 10.64898/2025.12.12.694020

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