Article
T cell phenotypes in patients with common variable immunodeficiency disorders: associations with clinical phenotypes in comparison with other groups with recurrent infections.
Clinical and experimental immunology - 1 Nov 2012
Bateman E A L, Ayers L, Sadler R, Lucas M, Roberts C, Woods A, Packwood K, Burden J, Harrison D, Kaenzig N, Lee M, Chapel H M, Ferry B L
Abstract excerpt
Common variable immunodeficiency disorders (CVID) are a group of heterogeneous conditions that have in common primary failure of B cell function, although numerous T cell abnormalities have been described, including reduced proliferative response and reduced regulatory T cells. This study compared the T cell phenotype of CVID patients subdivided into clinical phenotypes as well as patients with partial antibody...
Topics
- Adolescent
- Adult
- Agammaglobulinemia
- Aged
- Aged, 80 and over
- Antigens, CD
- B-Lymphocyte Subsets
- Cell Differentiation
- Child
- Child, Preschool