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Article

Heterogeneity of Liver Disease in Common Variable Immunodeficiency Disorders.

Frontiers in immunology - 1 Jan 2020

Pecoraro Antonio, Crescenzi Ludovica, Varricchi Gilda, Marone Giancarlo, Spadaro Giuseppe

Abstract excerpt

Common variable immunodeficiency (CVID) is the most frequent primary immunodeficiency (PID) in adulthood and is characterized by severe reduction of immunoglobulin serum levels and impaired antibody production in response to vaccines and pathogens. Beyond the susceptibility to infections, CVID encompasses a wide spectrum of clinical manifestations related to a complex immune dysregulation that also affects liver....

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Identifiers

PMID: 32184784
DOI: 10.3389/fimmu.2020.00338
PMCID: PMC7059194

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