Article

K-7174 protects against OA pathogenesis through blockade of the Zmiz1-GATA axis.

2020-11-05

Abstract excerpt

<h4>Background: </h4> and Purpose Osteoarthritis (OA) is a leading cause of disability and bears a large socioeconomic cost, but we lack an effective disease-modifying therapy. There is great need to identify novel target molecules in OA pathogenesis. Here, by asking why old cartilage appears to be more sensitive to OA pathogenic factors, we identified the importance and underlying mechanism of K-7174 as a blocker...

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Literature Corpus work: d4b5aab8-dc0b-5539-b6bc-739cf0349ae9
DOI: 10.22541/au.160456723.34275152/v1

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