Article

Liquid-to-solid phase transition of <i>oskar</i> RNP granules is essential for their function in the <i>Drosophila</i> germline

2021-04-01

Abstract excerpt

<h4>Summary</h4> Asymmetric localization of oskar RNP granules to the oocyte posterior is crucial for abdominal patterning and germline formation of the Drosophila embryo. We show that oskar RNP granules in the oocyte are condensates with solid-like physical properties. Using purified oskar RNA and scaffold proteins Bruno and Hrp48, we confirm in vitro that oskar granules undergo a liquid-to-solid phase tra...

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Literature Corpus work: d4b54485-ad68-5405-b029-73a322347e82
DOI: 10.1101/2021.03.31.437848

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