Article

TimeFlow: a density-driven pseudotime method for flow cytometry data analysis

2025-02-21

Abstract excerpt

Pseudotime methods order cells undergoing differentiation from the least to most differentiated. We developed TimeFlow, a new method for computing pseudotime in multi-dimensional flow cytometry datasets. TimeFlow tracks the differentiation path of each cell on a graph by following smooth changes in the cell population density. To compute the probability density function of the cells, it uses a normalizing flow mod...

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Literature Corpus work: d47d21f1-cd59-52ce-8540-87ee42b7de80
DOI: 10.1101/2025.02.16.638508

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