Article
Modeling and visualizing cell type switching.
Computational and mathematical methods in medicine - 1 Jan 2014
Ghaffarizadeh Ahmadreza, Podgorski Gregory J, Flann Nicholas S
Abstract excerpt
Understanding cellular differentiation is critical in explaining development and for taming diseases such as cancer. Differentiation is conventionally represented using bifurcating lineage trees. However, these lineage trees cannot readily capture or quantify all the types of transitions now known to occur between cell types, including transdifferentiation or differentiation off standard paths. This work...
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