Article

TimeFlow 2: an unsupervised cell lineage detection method for flow cytometry data

2025-11-03

Abstract excerpt

Cell lineage detection refers to the inference of differentiation pathways from immature cells to distinct mature cell types. We developed TimeFlow 2, a new method for lineage inference in large flow cytometry datasets. It uses a single static snapshot of unordered cells and does not require prior knowledge of the number of pathways, cell type or temporal labels. TimeFlow 2 uses the cell orderings from TimeFlow an...

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Literature Corpus work: 67f32211-869d-5f35-b01d-b5cd63ec82ab
DOI: 10.1101/2025.11.01.685988

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