Article

A mathematical framework for human neutrophil state transitions inferred from single-cell RNA sequence data

2025-07-02

Abstract excerpt

Neutrophils, the most abundant immune cells in the human circulation, play a central role in the innate immune system. While neutrophil heterogeneity is a topic of increasing research interest, few efforts have been made to model the dynamics of neutrophil population subsets. We develop a mathematical model to describe the dynamics that characterizes the states and transitions involved in the maturation of human n...

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Literature Corpus work: 0f61cb50-2b08-5d36-ada4-e480d9d297c3
DOI: 10.1101/2025.06.27.662068

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