Article
Multi-type branching models to describe cell differentiation programs.
Journal of theoretical biology - 21 May 2011
Nordon Robert E, Ko Kap-Hyoun, Odell Ross, Schroeder Timm
Abstract excerpt
Cell proliferation and differentiation is described by a multi-type branching process, a probability model that defines the inheritance of cell type. Cell type is defined by (i) a repression index related to the time required for S-phase entry and (ii) phenotype as determined by cell markers and division history. The inheritance of cell type is expressed as the expected number and type of progeny cells produced...
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