Article

SupeRJump: Determining normal and leukemic differentiation fate through semi-supervised jump diffusion modeling

2026-07-07

Abstract excerpt

<h4>ABSTRACT</h4> Single cell RNA-seq (scRNA) has provided unprecedented resolution into cellular and clonal heterogeneity. Computational approaches have enabled recovery of differentiation dynamics, yet current approaches do not evaluate discontinuous differentiation processes present in malignant leukemia. To address these gaps, we developed SupeRJump: a jump-drift-diffusion based supervised cell-fate model (...

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Literature Corpus work: 0e79fdbd-2f2a-5170-a6ed-b9e434cf7179
DOI: 10.64898/2026.07.01.735284

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