Article

Inferring Phylogenetic Trees of Cancer Evolution from Longitudinal Single-Cell Copy Number Profiles

2025-03-18

Abstract excerpt

Understanding evolutionary dynamics is critical for unraveling the complex progression of diseases such as cancer. Cancer evolution is inherently a temporal process driven by the accumulation of mutations and clonal expansions over time. Traditional phylogenetic methods often rely solely on static, cross-sectional data, limiting their ability to infer the timing of key evolutionary events. To address this challeng...

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Literature Corpus work: d44b232f-631f-528f-8ccb-b73737e4df39
DOI: 10.1101/2025.03.17.643834

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