Article

Joint inference of exclusivity patterns and recurrent trajectories from tumor mutation trees

2021-11-04

Abstract excerpt

Cancer progression is an evolutionary process shaped by both deterministic and stochastic forces. Multi-region and single-cell sequencing of tumors enable high-resolution reconstruction of the mutational history of each tumor and highlight the extensive diversity across tumors and patients. Resolving the interactions among mutations and recovering recurrent evolutionary processes may offer greater opportunities fo...

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Literature Corpus work: f503fcdc-54ea-59e6-99c6-5fae27177870
DOI: 10.1101/2021.11.04.467347

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