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Article

Mapping the plasma proteomic architecture of systemic lupus erythematosus

2025-11-19

Abstract excerpt

<h4>Summary</h4> Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterised by autoantibodies to nuclear antigens. SLE is highly heterogeneous, both clinically and immunologically, yet the molecular basis underlying this remains incompletely understood. To address this, we profiled the plasma proteome in 260 SLE patients and 86 healthy volunteers (HVs) using the SomaScan v4.1 platform, quan...

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Literature Corpus work
d407597a-e620-5c9a-ab81-242ecfa36fc4
DOI
10.1101/2025.11.14.25340226
Open publication

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Mapping the plasma proteomic architecture of systemic lupus erythematosusDOI 10.1101/2025.11.14.25340226
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