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Adults with systemic lupus exhibit distinct molecular phenotypes in a cross-sectional study

1 Mar 2020

Abstract excerpt

BACKGROUND: The clinical and pathologic diversity of systemic lupus erythematosus (SLE) hinders diagnosis, management, and treatment development. This study addresses heterogeneity in SLE through comprehensive molecular phenotyping and machine learning clustering. METHODS: = 13) were assessed by multiplex bead-based assays and ELISAs. Patient clusters were identified by machine learning combining K-means...

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PMID: 32154507
DOI: 10.1016/j.eclinm.2020.100291

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