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Transcriptomic studies unravel the molecular and cellular complexity of systemic lupus erythematosus: A review

16 Sept 2024

Abstract excerpt

Transcriptomic analysis plays a vital role in investigating Systemic Lupus Erythematosus (SLE), a complex autoimmune disease characterized by diverse clinical manifestations. This approach has yielded valuable insights into gene expression patterns and molecular regulatory mechanisms involved in SLE pathogenesis. Notably, interferon-stimulated gene (ISG) signatures are significantly upregulated in immune cells,...

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Atherosclerosis and Cardiovascular Diseases
Systemic Lupus Erythematosus Research
T-cell and B-cell Immunology

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39293718
DOI: 10.1016/j.clim.2024.110367

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