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Blood Genomics Identifies Three Subtypes of Systemic Lupus Erythematosus: “IFN‐High,” “NE‐High,” and “Mixed”

1 Jan 2021

Abstract excerpt

PURPOSE: Systemic lupus erythematosus (SLE) is a systemic and multifactorial autoimmune disease, and its diverse clinical manifestations affect molecular diagnosis and drug benefits. Our study was aimed at defining the SLE subtypes based on blood transcriptome data, analyzing functional patterns, and elucidating drug benefits. METHODS: Kinoid (IFN-K). Based on disease activity scores and gene expression data, we...

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PMID: 34305454
DOI: 10.1155/2021/6660164

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