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Article

Serum IgA autoantibody profiling in systemic lupus erythematosus reveals associations with disease phenotypes.

RMD open - 15 Jul 2026

Eades Laura E, Papadaki Artemis, Lennard Katie, Hoi Alberta Y, Kandane-Rathnayake Rangi, Morand Eric F, Figgett William A, Vincent Fabien B

Abstract excerpt

BACKGROUND: Knowledge of the role of IgA isotype autoantibodies in systemic lupus erythematosus (SLE) is lacking. We aimed to explore associations between serum IgA autoantibody profiles and SLE clinical phenotypes using an unbiased approach. METHODS: 1613 serum IgA autoantibodies were quantified in 60 patients with SLE using the i-Ome protein array, customised to also detect antibodies against three interferons...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42457208
DOI: 10.1136/rmdopen-2026-006811
PMCID: PMC13374403

Genes

STAM2
AMOTL2
TACC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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