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The NOTCH3 Downstream Target HEYL Regulates Human Airway Epithelial Club Cell Differentiation

2021-03-10

Abstract excerpt

Basal cells (BC) are the resident stem/progenitor cells of the adult pseudostratified airway epithelium, whose differentiation program is orchestrated by the NOTCH signaling pathway. NOTCH3 receptor mediated signaling regulates BC to club cell differentiation; however, the downstream responses that regulate this process are largely unknown. In the present study we used an in vitro air-liquid interface model of th...

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Literature Corpus work
d3d4ef5e-0f63-582b-9371-9836d79aa51b
DOI
10.1101/2021.03.10.434858
Open publication

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The NOTCH3 Downstream Target HEYL Regulates Human Airway Epithelial Club Cell DifferentiationDOI 10.1101/2021.03.10.434858
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