Article

Suspension-Based Human Esophagoids Recapitulate WNT2B-Dependent Regulation of Esophageal Basal Progenitors

2026-06-24

Abstract excerpt

<h4>Background & Aims</h4> The human esophagus undergoes a tightly regulated developmental program, transitioning from a simple columnar epithelium in early development to a mature stratified squamous tissue essential for adult barrier function. Here, we constructed a developmental cell atlas spanning early development to adulthood and leveraged it to generate physiologically relevant in vitro models. <h4>Metho...

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Literature Corpus work: 388caa92-0343-5536-a585-3abe6744edc2
DOI: 10.64898/2026.06.23.733451

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