Article

Human club cells derived from pluripotent stem cells reveal new insights into epithelial lineage plasticity through structural and functional validation

2026-05-22

Abstract excerpt

Airway epithelial homeostasis relies on multiple specialized cell types, with club cells playing central roles in maintaining epithelial integrity and regulating inflammation. Environmental insults such as allergens, viral infections, or pollutants preferentially damage club cells, impairing epithelial repair and contributing to pulmonary diseases. However, the functional properties of club cells remain incomplete...

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Literature Corpus work: b4be736e-e7ec-58c4-a1d6-b5408f08d0cf
DOI: 10.64898/2026.05.20.726364

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