Article
Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors
9 Jan 2015
Abstract excerpt
Basal cells are multipotent airway progenitors that generate distinct epithelial cell phenotypes crucial for homeostasis and repair of the conducting airways. Little is known about how these progenitor cells expand and transition to differentiation to form the pseudostratified airway epithelium in the developing and adult lung. Here, we show by genetic and pharmacological approaches that endogenous activation of...
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